Anti-Venom
Plot:
Spider-Man and Agent Venom have been cracking down at defeating possible Sinister Six recruits like Shocker, Grizzly, and Beetle. When Doctor Octopus (now paired up with Dr. Michael Morbius) has made an entirely new symbiotic that's corrosive to the original one, it takes control of Harry Osborn after he and and his team intervenes. The Anti-Venom symbiotic controls Harry into destroying Spider-Man and Agent Venom as the new Anti-Venom. Now Spider-Man and Agent Venom must work with Iron Patriot to free Harry from the Anti-Venom symbiotic.